Freddie Moreno had finally escaped from the raucous house of women with whom he grew up. Having achieved some success as head chef at a trendy Chicago restaurant, he's ready for love and everything else that single life has to offer, including hanging out with his best friend and neighbor, Chris. Unfortunately, there's one slight hitch: After the death of his older brother and the collapse of his sister's marriage, goodhearted Freddie took in his impulsive sister-in-law, his pragmatic sister with her 13-year-old daughter and their irascible grandma, who refuses to speak English and only responds in Spanish – even though she understands every word. But while the members of this unconventional brood may test Freddie's patience endlessly, they also support and take care of one another, just as they always have. Now all Freddie has to do is figure out how to maintain his thriving bachelor lifestyle in a house overflowing with estrogen.

It's a brand new life for Cory Baxter when his dad, Victor, becomes the personal chef to the President of the United States. Cory's entrepreneurial scheming reaches new heights as he mingles amongst high-powered Washington D.C. elite.

Four turtles fall into the sewers and are befriended by Hamato Yoshi a Japanese man sent to New York who was forced to live in the sewers. One day he sees a strange green glow which transforms the four turtles into human-like creatures. Hamato (now Master Splinter) changes into a giant rat from the green glow and teaches the turtles the skills of the ninja as they team up with news reporter April O'Neil to battle against Yoshi's arch enemy Shredder and Krang, an alien warlord from Dimension X.