A brilliant medical practitioner finds himself at the centre of a murder plot after taking the daughter of a Russian Police Commissioner back to his hotel room.

Karthik meets Deepika during a flight to Melbourne and they become friends. On reaching Australia, Karthik realises that Deepika works in the same firm as his ex-lover Jhansi.

Gurupadam, a ganglord, kicks out his driver due to certain accusations against him. The driver's son, Burma, grows up and joins the boss's gang with revenge on his mind.

Unemployed Shakthi Singh lives a poor lifestyle along with his widowed and ailing mother and a sister. His mother falls ill and gets admitted in hospital. While on his way to an interview with HSBC, Shakthi sees a beautiful girl, gets distracted and misses his bus - route No.12B. As a result he misses the interview, and ends up getting employed as a Garage Mechanic with Madan, his friend. He does meet with the same girl, gets to know her name is Jyotika, who lives a wealthy lifestyle with her mother, Sulo, while her dad is away on business. Both continue meeting not aware that her marriage has been arranged with Pratap. This story also depicts the possibility of Shakthi catching the 12B on time, attending the interview and getting hired, pursuing Jyotika in vain, and ending up in the arms of his co-worker, Priya. Both possibilities end up with Shakthi getting involved in a vehicle accident - and no guarantees that he will survive or wed Jyotika.