Gharana Mogudu is a remake of tamil movie Mannan and it is a drama based movie in which, Raju (Chiranjeevi) is a do-gooder who helps his fellow co-workers while working in Visakhapatnam shipyard, but when his mother suffers a paralytic stroke, he moves back to Hyderabad and looks for a job.Uma Devi (Nagma) daughter of industrialist Bapineedu (Raogopal Rao) takes over the business from her father and helps it to reach new heights which also sees her head strongness reach new heights as well. In this scenario, she not only rejects Ranganayakulu

Raghupathi (Murali Mohan), Raghava (Sarath Kumar) and Rajaram (Chiranjeevi) are brothers. Raghupathi is the only employee of the family. Raghava is preparing for Civil Service Examation and Rajaram is an unemployee. Rajaram and his four friends are a gang and are searching for jobs daily. They roam in the city till mid-night. Rajaram comes home at mid-night and sleeps till afternoon, his grand mother (Nirmalamma) scolds him for his irresponsibility and carelessness. On oneday Rajaram makes Kanya Kumari (Vijayashanti) to leave the house as she is not paying the rent to the house, Subsequently she changed her place to Rajaram's (Chiranjeevi) house. At one situation Rajaram (Chiranjeevi) goes to jail for money, because his brother requires money as he wants to go to Delhi for IAS preparation. Ekambaram (Raogopal Rao) kills Raghupathi (Murali Mohan) while his brother (Raja Ram) is in jail , but Rajarams` friends know how he died. Rajaram thinks his brother's death was an accident.