Luna Kunath (Caroline Erikson) and Tamara Meurer (Anjua Pahl) work together in the Potsdam murder commission. Luna is single, strong, assertive, funny, empathic, sporty and fast in the head. It is an excellent policewoman whose carefree always accompanies with a little naivety and brings you again and again in brenzy situations. Tamara, however, has more mature, adult. The two of the boss Bernhard Henschel (Michael Lott) and the colleagues David Grünbaum (Omar El-Saeidi), Christoph Westermann (Hendrik von Bültzingslöwen), lail-sure Thomas Brandner (Yung No) and legal physician Werner Vense (Bernd Stegemann). Potsdam, Berlin's pretty little sister, confronts the commissars again and again with a wide variety of life effects. However, the team not only determines in Potsdam, but must always be out of the surrounding area. Because the crime does not stop at the city limit.

Best buddies Christian Ulmen and Fahri Yardim can't help to embarrass themselves from time to time. The troublemakers they are they love to test the limits of ethics and political correctness.