Hairi (Saiful Apek) is a loser who lives in Metrofulus. While working in the lab, he accidentally drinks coffee that has been contaminated by a virus-infected gecko. He soon finds himself doing the most insane things, such as sticking to walls, making chirping cicak noises and adding bugs to his menu. He turns to his best friend and apartment mate, Danny (Yusry Abdul Halim), and begs him to find the reason behind his strange antics. Meanwhile, the people of Metrofulus are constantly being infected by new strains of viruses, and the only cure seems to come only from Professor Klon's (Aznil Nawawi) lab. Suspecting something amiss, Hairi and Danny launch their own investigation and discover that Professor Klon is not only the creator of such viruses, but also has a more sinister plan up his sleeve, backed by his business partners, the Ginger Boys Ramlie and AC Mizal, who first tend to take revenge on Professor Klon's failed experiment on them; making their senses turn abnormal.

The story starts with Hakimi, a freelance scriptwriter who is on his way to send his 7-year-old daughter, Imelda, to his ex-wife's house on one stormy night. On the way there, he sees a sports car that just hit a tree. Hakimi stops his car and sees a girl is trapped in the car. He decides to help the girl, who is very badly hurt, and leaves her after calling the ambulance. He also doesn't realize that he accidentally left one of his shoes there. Meanwhile, Puteri Megawati, who is very thankful to the mysterious guy that saved her, meets Siti Shahirah, a member of the paparazzi that as usual, is looking for sensational news. The princess asks Siti to help her look for "Mr. Cinderella" (the man that helped her that night) and promises a reward of RM500,000. Who's the real "Mr. Cinderella"?