Sawada Kyoka is a yoga instructor with a rough personality and constantly fights with her father after her mother passed away. Due to having to spend the time taking care of her father, Kyoka doesn't have much time for herself and has very little desire to get married. Meanwhile, Sawada Rintaro is Kyoka's father and works as a freelance lexicographer. After the passing of his wife, Rintaro hasn't been living well which frustrates Kyoka. One day, Rintaro decides to find his second life partner and wants to start a "double marriage life" with Kyoka.

In the end of Meiji era, Takei Chiyo was born in a poor family in Osaka, and was sent to a theatre tea room as a servant when she was 9 years old. There, she was attracted by the world of theatre comedy. She grows up to be an actor and marries to Amami Ippei , but the war broke out and she was forced to stay away from acting for a while. However, when she comes back again, her acting in a radio drama impresses many people and makes herself one of the leading actors in western Japan.

A consultant who has a superhuman sense of smell and assists in solving cases by smelling the scents left behind at crime scenes. He usually lives with a nasal plug, but once he removes it, and takes one sniff with his keen sense of smell, he will know the person’s age, gender, what he or she ate and even lifestyle. Besides investigating cases, he is researching whether people’s emotions have scent too. He has a daughter with Katayama Megumi.

Toho university hospital has established an outstanding coronary surgery team under the leadership of a up and coming, star, U.S. trained surgeon that specializes in the highly risky "Batista" procedure to shrink the size of enlarged hearts. Normally this procedure has only a 60% success rate, but "Team Batista" has achieved a run of 26 straight successes....when suddenly 3 patients in a row die on the operating table. Very disturbed, the lead surgeon requests an independent investigation. The hospital turns to Dr. Taguchi who is a specialist in psychosomatic disorders who is shocked to at the assignment because she knows nothing in particular about surgery. Assured, however, that this very lack of insider specialized knowledge is in fact the "objectivity" required, she diligently begins to investigate in her own polite, but persistent manner.

Newspaper correspondent Kyoko Togakure visits a nursing home in the outskirts of Tokyo. She finds the dead body of a resident. It was an apparent suicide. He's holding a piece of paper with the mystifying word "Death Water" written on it. Nearby are blood-stained scissors, and his eyes are squashed. She has no idea that this death is just the beginning of a horrendous nightmare.