Joey Wellman, an American cartoonist from Cleveland now largely forgotten at home, visits France with his partner Lena to attend an exhibition in Paris about the comic strip (bande dessinée) which features his work. He also hopes to be reconciled with his daughter Elsie who has been a student in Paris for two years, in flight from the American culture of which she sees her father as a typical example. Elsie is naively infatuated with French literature, and is trying to secure an introduction to the brilliant university professor Christian Gauthier, an expert on Flaubert but also an enthusiast for comic books. The meeting of father and daughter goes badly, but Elsie is persuaded to join Joey and Lena for the weekend at the country house of Gauthier's mother, Isabelle. During a comic-themed masquerade party, all of the characters are made to reconsider their present and past relationships.

Insulted when his screenwriter wife writes a leading role for a younger man, aging Broadway idol Fitz Wynn disguises himself as a handsome young Italian.

Fledgling comic Benjy Stone can't believe his luck when his childhood hero, the swashbuckling matinee idol Alan Swann, gets booked to appear on the variety show he writes for. But when Swann arrives, he fails to live up to his silver screen image. Instead, he's a drunken womanizer who suffers from stage fright. Benjy is assigned to look after him before the show, and it's all he can do to keep his former idol from going completely off the rails.

A group of scientists take Simon, a psychology professor, as a test person for a brainwashing experiment and try to convince him that he is a living being from another planet.