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After a night of heavy drinking, Jeanne and Deb take an empty road through the backwoods to avoid traffic where they unexpectedly hit a mysterious woman that quickly vanishes into a field. Plagued with guilt and unable to go to the police, the girls decide to investigate with the help of some friends. But when their peers start to die or inexplicably vanish, it becomes clear that a bigger, sinister force is at work as Jeanne is thrown into a bizarre conflict with the undead and a sinister voodoo priest with malicious intentions.
