In the midst of his crumbling relationship, a radio show host begins speaking to his biggest fan—a young boy—via the telephone. But when questions about the boy's identity come up, the host's life is thrown into chaos.

Zed is an American vault-cracker who travels to Paris to meet up with his old friend Eric. Eric and his gang have planned to raid the only bank in the city which is open on Bastille day. After offering his services, Zed soon finds himself trapped in a situation beyond his control when heroin abuse, poor planning and a call-girl named Zoe all conspire to turn the robbery into a very bloody siege.

After a friend overdoses, Spoon and Stretch decide to kick their drug habits and attempt to enroll in a government detox program. Their efforts are hampered by seemingly endless red tape, as they are shuffled from one office to another while being chased by drug dealers and the police.

It's autumn in New York. Sam has broken up with his girlfriend and his father has recently died. World-weary and sloppy drunk, he finds temporary solace in the arms of Anna, a mysterious vampire who draws him away from his friends and into a web of addiction and madness.

Stefan, a young gay East German medical student, arrives in San Francisco for a medical congress and is following the trail of his dead father, a once high ranking AIDS researcher in the East. Stefan is investigating whether the HIV virus was an incremental result of secret human experiments that were conducted in US prisons in the seventies - a thesis of the Berlin professor, Jakob Segal, which was spread by state agents of former East Germany. At the same time, a serial killer is haunting the gay bars of the city and is killing HIV positive long-term survivors.

An incestuous and industrious pair of modern-day vampires finds their clever manner of acquiring sustenance threatened by a nosy New Jersey health inspector and a determined investigative reporter in director John Orrichio's sexualized tale of life among the undead. The LeGaults know well that to stalk the streets for prey is to leave themselves open to exposure. Instead of seeking out blood the old-fashioned way, the LeGaults opt to open a blood donation center that will provide them with the nourishment they need to survive without the risks that go along with using their fangs. A New Jersey health inspector named Jerry is on to them, though, and along with a little help from intrepid reporter Phyllis, he soon prepares to rip the lid off of the LeGault's bizarre scam. When a chance encounter with two students of the occult reveals the true motivation behind the LeGaults' philanthropic front...